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浙江师范大学，化学与生命科学学院，“双龙学者”特聘教授，硕士生导师
Email: liuyangzi@zjnu.edu.cn，办公室：7幢410
教育经历
2020.1-2021.12 | 博士后 | 中科院上海有机所 | 合作导师：游书力研究员 |
2015.9-2019.12 | 博士 | 华东理工大学 | 导师：邓卫平教授 |
2012.9-2015.6 | 硕士 | 华东理工大学 | 导师：邓卫平教授 |
2008.9-2012.6 | 本科 | 华东理工大学 | 导师：邓卫平教授 |
工作经历
2022.01-至今 “双龙学者”特聘教授, 浙江师范大学化学与生命科学学院
研究方向
不对称环加成反应
基于新方法的手性药物绿色合成及工艺开发
主持和参与项目
第68批中国博士后科学基金面上项目 2020M681439，8万，主持 (已结题)
国家自然科学基金委重点项目 22031012， 300万，参与 (在研)
国家自然科学基金委面上项目 21971062， 66万，参与 (在研)
发表文章
Liu Yang-Zi, Song Hao, Zheng ?Chao, You Shu-Li. Cascade Asymmetric Dearomative Cyclization Reactions via Transition-Metal-Catalysis. Nature Synthesis2022, https://doi.org/10.1038/s44160-022-00039-y. (accept)
Liu Yang-Zi*, Wang Zhongao, Huang Zesheng, Yang Wu-Lin, and Deng Wei-Ping. Sulfone as a Transient Activating Group in the Palladium-Catalyzed Asymmetric [4 + 3] Cycloaddition of Trimethylenemethane Enabling the Enantioselective Synthesis of Fused Azepines. Org. Lett.2021, 23, 948-952.
Liu Yang-Zi, Wang Zhongao, Huang Zesheng, Zheng Xing, Yang Wu-Lin, and Deng Wei-Ping. Palladium-Catalyzed Asymmetric [4 + 3] Cyclization of Trimethylenemethane: Regio-, Diastereo-, and Enantioselective Construction of Benzofuro[3,2-b]azepine Skeletons. Angew. Chem. Int. Ed. 2020, 59, 1238-1242.
Liu Yang-Zi, Shang Shao-Jing, Zhu Jing-Yan, Yang Wu-Lin, Deng Wei-Ping. Regioselective and Stereoselective [3 + 3] Annulation of Ketones Derived Azomethine Ylides with 2-Indolylethylenes: Direct Access to Highly Substituted Tetrahydro-γ-Carbolines. Adv. Synth. Catal., 2018, 360, 2191-2203.
Liu Yang-Zi,? Shang Shao-Jing,? Yang Wu-Lin, Luo Xiaoyan, Deng Wei-Ping.Stereoselective Synthesis of Pyrrolidines Containing a 3 Fluoro Quaternary Stereocenter via Copper(I)-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition. J. Org. Chem., 2017, 82, 11141-11149.
Zou Xuejie, Liu Yang-Zi, Shang Shaojing, Yang Wulin,Deng Wei-Ping. Diastereoselective Synthesis of Functionalized Tetrahydro-γ-Carbolines via a [3 + 3] Cycloaddition of 2,2'-Diester Aziridines with β-(Indol-2-yl)-α,β-unsaturated Ketones. Chin. Chem. Lett.,2019, 31, 1293-1296.
Yang Wu-Lin, Liu Yang-Zi, Luo Shuai, Yu Xingxin, Fossey John S.,Deng Wei-Ping.Copper-catalyzed asymmetric construction of dispiropyrrolidine skeleton via 1,3-dipolarcycloaddition of azomethine ylides with α-alkylidene. Chem. Commun., 2015, 51, 9212-9215.
Yang Wu-Lin, Huang Zesheng, Liu Yang-Zi, Yu Xingxin, Deng Wei-Ping. Highly Regio-, Diastereo-, and Enantioselective Assembly of Azepino[2,3 b]indoles via Palladium-Catalyzed [4 + 3] Cycloaddition. Chin. J. Chem., 2020, 38, 1571-1574.
Zheng Xing, Yang Wu-Lin, Liu Yang-Zi, Wu Shu-Xiao,Deng Wei-Ping. Enantioselective Synthesis of Tropanes via [3 + 3] Annulation of Cyclic Azomethine Ylides with Substituted 2-Vinylindoles and 2-Vinylpyrroles. Adv. Synth. Catal., 2018, 360, 2843-2853.
Zhu Jing-Yan, Yang Wu-Lin, Liu Yang-Zi, Shang Shao-Jing, Deng Wei-Ping. Copper(I)-catalyzed Asymmetric Mannich Reaction of Glycine Schiff Bases with Isatin-derived Ketimines: Enantioselective Synthesis of 3-Substituted 3-Aminooxindoles. Org. Chem. Front., 2018, 5, 70-74.
Wang Zheng, Ye Jinjin, Wu Rui, Liu Yang-Zi, Fossey John S., Cheng Jiagao, Deng Wei-Ping. Bi-Aryl Rotation in Phenyl-dihydroimidazoquinoline Catalysts for Kinetic Resolution of Arylalkyl Carbinols. Catal. Sci. Technol., 2014, 4, 1909-1913.
Wang Zheng, Luo Shuai, Zhang Shoude, Yang Wu-Lin, Liu Yang-Zi, Li Honglin, Luo Xiaoyan, Deng Wei-Ping. Catalytic Asymmetric Construction of Quaternary ?-Amino Acid-Containing Pyrrolidines via 1,3-Dipolar Cycloaddition of Azomethine Ylides to ?-Aminoacrylates. Chem. Eur. J., 2013, 19, 6739-6745.
Wang Zheng, Yu Xingxin, Tian Bo-Xue, Payne Daniel T., Yang Wu-Lin, Liu Yang-Zi, Fossey John S., Deng Wei-Ping.Chiral N,O-Ligand/Cu(OAc)2 Catalyzed Asymmetric Construction of 4-Aminopyrrolidine Derivatives via 1,3-Dipolar Cycloaddition of Azomethine Ylides with α-phthalimidoacrylates. Chem. Eur. J., 2015, 21, 10457-10465.
